Upregulation of TMEM16A Protein in Bronchial Epithelial Cells by Bacterial Pyocyanin

Induction of mucus hypersecretion in the airway epithelium by Th2 cytokines is associated with the expression of TMEM16A, a Ca(2+)-activated Cl(-) channel. We asked whether exposure of airway epithelial cells to bacterial components, a condition that mimics the highly infected environment occurring...

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Veröffentlicht in:PLoS One
Hauptverfasser: Caci, Emanuela, Scudieri, Paolo, Di Carlo, Emma, Morelli, Patrizia, Bruno, Silvia, De Fino, Ida, Bragonzi, Alessandra, Gianotti, Ambra, Sondo, Elvira, Ferrera, Loretta, Palleschi, Alessandro, Santambrogio, Luigi, Ravazzolo, Roberto, Galietta, Luis J. V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486680/
https://ncbi.nlm.nih.gov/pubmed/26121472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131775
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