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Models in biology: lessons from modeling regulation of the eukaryotic cell cycle

In this essay we illustrate some general principles of mathematical modeling in biology by our experiences in studying the molecular regulatory network underlying eukaryotic cell division. We discuss how and why the models moved from simple, parsimonious cartoons to more complex, detailed mechanisms...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:BMC Biol
Hauptverfasser: Tyson, John J., Novák, Béla
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486427/
https://ncbi.nlm.nih.gov/pubmed/26129844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-015-0158-9
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