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Models in biology: lessons from modeling regulation of the eukaryotic cell cycle

In this essay we illustrate some general principles of mathematical modeling in biology by our experiences in studying the molecular regulatory network underlying eukaryotic cell division. We discuss how and why the models moved from simple, parsimonious cartoons to more complex, detailed mechanisms...

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Dades bibliogràfiques
Publicat a:BMC Biol
Autors principals: Tyson, John J., Novák, Béla
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486427/
https://ncbi.nlm.nih.gov/pubmed/26129844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-015-0158-9
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