Regulation of CD44E by DARPP-32-dependent activation of SRp20 splicing factor in gastric tumorigenesis

OBJECTIVE: CD44E is a frequently overexpressed variant of CD44 in gastric cancer. Mechanisms that regulate CD44 splicing and expression in gastric cancer remain unknown. Herein, we investigated the role of DARPP-32 (dopamine and cAMP-regulated phosphoprotein, Mr 32000) in promoting tumor growth thro...

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Udgivet i:Oncogene
Main Authors: Zhu, Shoumin, Chen, Zheng, Katsha, Ahmed, Hong, Jun, Belkhiri, Abbes, El-Rifai, Wael
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486340/
https://ncbi.nlm.nih.gov/pubmed/26119931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.250
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