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Stable Isotope Resolved Metabolomics Analysis of Ribonucleotide and RNA Metabolism in Human Lung Cancer Cells

We have developed a simple NMR-based method to determine the turnover of nucleotides and incorporation into RNA by stable isotope resolved metabolomics (SIRM) in A549 lung cancer cells. This method requires no chemical degradation of the nucleotides or chromatography. During cell growth, the free ri...

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Bibliografiske detaljer
Udgivet i:Metabolomics
Main Authors: Fan, Teresa W-M., Tan, Jinlian, McKinney, Martin M., Lane, Andrew N.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486296/
https://ncbi.nlm.nih.gov/pubmed/26146495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11306-011-0337-9
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