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Stable Isotope Resolved Metabolomics Analysis of Ribonucleotide and RNA Metabolism in Human Lung Cancer Cells

We have developed a simple NMR-based method to determine the turnover of nucleotides and incorporation into RNA by stable isotope resolved metabolomics (SIRM) in A549 lung cancer cells. This method requires no chemical degradation of the nucleotides or chromatography. During cell growth, the free ri...

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Bibliografske podrobnosti
izdano v:Metabolomics
Main Authors: Fan, Teresa W-M., Tan, Jinlian, McKinney, Martin M., Lane, Andrew N.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486296/
https://ncbi.nlm.nih.gov/pubmed/26146495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11306-011-0337-9
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