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New role for antigen-presenting activated pDCs in promoting Th17 cells and impacting antitumor immunity

Plasmacytoid dendritic cells (pDCs) are not only potent inflammatory cytokine producers but also function as antigen-presenting cells (APCs). We have shown that vaccination using CpG-B activated tumor antigen (Ag) presenting pDCs induce Th17 cells that promote intratumoral immune cell recruitment, i...

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Опубликовано в: :Oncoimmunology
Главные авторы: Guéry, Leslie, Hugues, Stéphanie
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485838/
https://ncbi.nlm.nih.gov/pubmed/26155409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/2162402X.2014.988476
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