Cargando...
Deciphering the genetic evolution of T-cell resistance in melanoma
T–cell-based immunotherapy of melanoma becomes ineffective when β2m-deficient tumor cells of a human leukocyte antigen (HLA) class I-negative phenotype grow out. We demonstrated that an early-acquired chromosomal deletion and subsequent inactivating gene mutation lead to β2m deficiency, suggesting t...
Gardado en:
| Publicado en: | Oncoimmunology |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Taylor & Francis
2015
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4485751/ https://ncbi.nlm.nih.gov/pubmed/26155406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1005510 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|