The genetic evolution of treatment-resistant cutaneous, acral and uveal melanomas

PURPOSE: Melanoma is a biologically heterogeneous disease composed of distinct clinicopathologic subtypes that frequently resist treatment. To explore the evolution of treatment resistance and metastasis, we used a combination of temporal and multi-lesional tumor sampling in conjunction with whole e...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Makohon-Moore, Alvin P., Lipson, Evan J., Hooper, Jody E., Zucker, Amanda, Hong, Jungeui, Bielski, Craig M., Hayashi, Akimasa, Tokheim, Collin, Baez, Priscilla, Kappagantula, Rajya, Kohutek, Zachary, Makarov, Vladimir, Riaz, Nadeem, Postow, Michael A., Chapman, Paul B., Karchin, Rachel, Socci, Nicholas D., Solit, David B., Chan, Timothy A., Taylor, Barry, Topalian, Suzanne L., Iacobuzio-Donahue, Christine A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7925434/
https://ncbi.nlm.nih.gov/pubmed/33323400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-2984
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