The genetic evolution of treatment-resistant cutaneous, acral and uveal melanomas

PURPOSE: Melanoma is a biologically heterogeneous disease composed of distinct clinicopathologic subtypes that frequently resist treatment. To explore the evolution of treatment resistance and metastasis, we used a combination of temporal and multi-lesional tumor sampling in conjunction with whole e...

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Опубликовано в: :Clin Cancer Res
Главные авторы: Makohon-Moore, Alvin P., Lipson, Evan J., Hooper, Jody E., Zucker, Amanda, Hong, Jungeui, Bielski, Craig M., Hayashi, Akimasa, Tokheim, Collin, Baez, Priscilla, Kappagantula, Rajya, Kohutek, Zachary, Makarov, Vladimir, Riaz, Nadeem, Postow, Michael A., Chapman, Paul B., Karchin, Rachel, Socci, Nicholas D., Solit, David B., Chan, Timothy A., Taylor, Barry, Topalian, Suzanne L., Iacobuzio-Donahue, Christine A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7925434/
https://ncbi.nlm.nih.gov/pubmed/33323400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-2984
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