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Retrieval of functional TCRs from single antigen-specific T cells: Toward individualized TCR-engineered therapies
We have developed a highly versatile platform for the systematic retrieval of T-cell receptors (TCRs) from single-antigen-reactive T cells and for characterization of their function and specificity. This approach enables rapid extraction of multiple TCRs from repertoires in individuals and not only...
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Publicado no: | Oncoimmunology |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Taylor & Francis
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4485745/ https://ncbi.nlm.nih.gov/pubmed/26140230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1005523 |
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