The First Example of a Nitrile Hydratase Model Complex that Reversibly Binds Nitriles

Nitrile hydratase (NHase) is an iron-containing metalloenzyme that converts nitriles to amides. The mechanism by which this biochemical reaction occurs is unknown. One mechanism that has been proposed involves nucleophilic attack of an Fe-bound nitrile by water (or hydroxide). Reported herein is a f...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Am Chem Soc
Prif Awduron: Shearer, Jason, Jackson, Henry L., Schweitzer, Dirk, Rittenberg, Durrell K., Leavy, Tanya M., Kaminsky, Werner, Scarrow, Robert C., Kovacs, Julie A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2002
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485622/
https://ncbi.nlm.nih.gov/pubmed/12236756
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