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The First Example of a Nitrile Hydratase Model Complex that Reversibly Binds Nitriles
Nitrile hydratase (NHase) is an iron-containing metalloenzyme that converts nitriles to amides. The mechanism by which this biochemical reaction occurs is unknown. One mechanism that has been proposed involves nucleophilic attack of an Fe-bound nitrile by water (or hydroxide). Reported herein is a f...
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Publicado no: | J Am Chem Soc |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2002
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4485622/ https://ncbi.nlm.nih.gov/pubmed/12236756 |
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