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CaMKII inhibition ameliorates arrhythmias elicited by junctin ablation under stress conditions
BACKGROUND: Aberrant calcium signaling is considered as one of the key mechanisms contributing to arrhythmias, especially in the context of heart failure. In human heart failure, there is significant down-regulation of the sarcoplasmic reticulum protein junctin and junctin deficiency in mice is asso...
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| Veröffentlicht in: | Heart Rhythm |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4485547/ https://ncbi.nlm.nih.gov/pubmed/25814413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2015.03.043 |
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