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Implications of pleiotropy: challenges and opportunities for mining Big Data in biomedicine
Pleiotropy arises when a locus influences multiple traits. Rich GWAS findings of various traits in the past decade reveal many examples of this phenomenon, suggesting the wide existence of pleiotropic effects. What underlies this phenomenon is the biological connection among seemingly unrelated trai...
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| Publicat a: | Front Genet |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Frontiers Media S.A.
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4485215/ https://ncbi.nlm.nih.gov/pubmed/26175753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2015.00229 |
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