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Implications of pleiotropy: challenges and opportunities for mining Big Data in biomedicine

Pleiotropy arises when a locus influences multiple traits. Rich GWAS findings of various traits in the past decade reveal many examples of this phenomenon, suggesting the wide existence of pleiotropic effects. What underlies this phenomenon is the biological connection among seemingly unrelated trai...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Yang, Can, Li, Cong, Wang, Qian, Chung, Dongjun, Zhao, Hongyu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485215/
https://ncbi.nlm.nih.gov/pubmed/26175753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2015.00229
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