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Implications of pleiotropy: challenges and opportunities for mining Big Data in biomedicine

Pleiotropy arises when a locus influences multiple traits. Rich GWAS findings of various traits in the past decade reveal many examples of this phenomenon, suggesting the wide existence of pleiotropic effects. What underlies this phenomenon is the biological connection among seemingly unrelated trai...

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Bibliografski detalji
Izdano u:Front Genet
Glavni autori: Yang, Can, Li, Cong, Wang, Qian, Chung, Dongjun, Zhao, Hongyu
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485215/
https://ncbi.nlm.nih.gov/pubmed/26175753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2015.00229
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