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Transcriptional modulator ZBED6 affects cell cycle and growth of human colorectal cancer cells
The transcription factor ZBED6 (zinc finger, BED-type containing 6) is a repressor of IGF2 whose action impacts development, cell proliferation, and growth in placental mammals. In human colorectal cancers, IGF2 overexpression is mutually exclusive with somatic mutations in PI3K signaling components...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4485122/ https://ncbi.nlm.nih.gov/pubmed/26056301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1509193112 |
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