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Dopamine’s Actions in Primate Prefrontal Cortex: Challenges for Treating Cognitive Disorders

The prefrontal cortex (PFC) elaborates and differentiates in primates, and there is a corresponding elaboration in cortical dopamine (DA). DA cells that fire to both aversive and rewarding stimuli likely project to the dorsolateral PFC (dlPFC), signaling a salient event. Since 1979, we have known th...

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Detalles Bibliográficos
Publicado en:Pharmacol Rev
Main Authors: Arnsten, Amy F. T., Wang, Min, Paspalas, Constantinos D.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485014/
https://ncbi.nlm.nih.gov/pubmed/26106146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pr.115.010512
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