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Nicotinic α7 receptors enhance NMDA cognitive circuits in dorsolateral prefrontal cortex

The cognitive function of the highly evolved dorsolateral prefrontal cortex (dlPFC) is greatly influenced by arousal state, and is gravely afflicted in disorders such as schizophrenia, where there are genetic insults in α7 nicotinic acetylcholine receptors (α7-nAChRs). A recent behavioral study indi...

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Hlavní autoři: Yang, Yang, Paspalas, Constantinos D., Jin, Lu E., Picciotto, Marina R., Arnsten, Amy F. T., Wang, Min
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718126/
https://ncbi.nlm.nih.gov/pubmed/23818597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1307849110
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