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A secreted factor represses cell proliferation in Dictyostelium

Many cells appear to secrete factors called chalones that limit their proliferation, but in most cases the factors have not been identified. We found that growing Dictyostelium cells secrete a 60 kDa protein called AprA for autocrine proliferation repressor. AprA has similarity to putative bacterial...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Brock, Debra A., Gomer, Richard H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484793/
https://ncbi.nlm.nih.gov/pubmed/16176950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.02032
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