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Dictyostelium cells bind a secreted autocrine factor that represses cell proliferation

BACKGROUND: Dictyostelium cells secrete the proteins AprA and CfaD. Cells lacking either AprA or CfaD proliferate faster than wild type, while AprA or CfaD overexpressor cells proliferate slowly, indicating that AprA and CfaD are autocrine factors that repress proliferation. CfaD interacts with AprA...

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Bibliografiske detaljer
Main Authors: Choe, Jonathan M, Bakthavatsalam, Deenadayalan, Phillips, Jonathan E, Gomer, Richard H
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644720/
https://ncbi.nlm.nih.gov/pubmed/19187549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-10-4
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