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A Dictyostelium chalone uses G proteins to regulate proliferation

BACKGROUND: Several studies have shown that organ size, and the proliferation of tumor metastases, may be regulated by negative feedback loops in which autocrine secreted factors called chalones inhibit proliferation. However, very little is known about chalones, and how cells sense them. We previou...

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Autors principals: Bakthavatsalam, Deenadayalan, Choe, Jonathan M, Hanson, Nana E, Gomer, Richard H
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726123/
https://ncbi.nlm.nih.gov/pubmed/19635129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-7-44
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