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A Dictyostelium chalone uses G proteins to regulate proliferation

BACKGROUND: Several studies have shown that organ size, and the proliferation of tumor metastases, may be regulated by negative feedback loops in which autocrine secreted factors called chalones inhibit proliferation. However, very little is known about chalones, and how cells sense them. We previou...

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Bibliographic Details
Main Authors: Bakthavatsalam, Deenadayalan, Choe, Jonathan M, Hanson, Nana E, Gomer, Richard H
Format: Artigo
Language:Inglês
Published: BioMed Central 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726123/
https://ncbi.nlm.nih.gov/pubmed/19635129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-7-44
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