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A Dictyostelium Secreted Factor Requires a PTEN-Like Phosphatase to Slow Proliferation and Induce Chemorepulsion

In Dictyostelium discoideum, AprA and CfaD are secreted proteins that inhibit cell proliferation. We found that the proliferation of cells lacking CnrN, a phosphatase and tensin homolog (PTEN)-like phosphatase, is not inhibited by exogenous AprA and is increased by exogenous CfaD. The expression of...

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Detaylı Bibliyografya
Asıl Yazarlar: Herlihy, Sarah E., Tang, Yitai, Gomer, Richard H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595242/
https://ncbi.nlm.nih.gov/pubmed/23555023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059365
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