Simvastatin prevents isoproterenol-induced cardiac hypertrophy through modulation of the JAK/STAT pathway

Simvastatin (SIM) is a lipid-soluble inhibitor of hydroxy-3-methylglutaryl coenzyme A reductase with multiple reported therapeutic benefits. The present study was designed to investigate the effect of pretreatment with SIM on isoproterenol (ISO)-induced cardiac hypertrophy in rats. Twenty-four male...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Drug Des Devel Ther
Päätekijät: Al-rasheed, Nouf M, Al-Oteibi, Maha M, Al-Manee, Reem Z, Al-shareef, Sarah A, Al-Rasheed, Nawal M, Hasan, Iman H, Mohamad, Raeesa A, Mahmoud, Ayman M
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Dove Medical Press 2015
Aiheet:
Original Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484667/
https://ncbi.nlm.nih.gov/pubmed/26150695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S86431
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia