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Sitagliptin attenuates cardiomyopathy by modulating the JAK/STAT signaling pathway in experimental diabetic rats

Sitagliptin, a dipeptidyl peptidase-4 inhibitor, has been reported to promote cardioprotection in diabetic hearts by limiting hyperglycemia and hyperlipidemia. However, little is known about the involvement of the Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway modul...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Drug Des Devel Ther
Hauptverfasser: Al-Rasheed, Nouf M, Al-Rasheed, Nawal M, Hasan, Iman H, Al-Amin, Maha A, Al-Ajmi, Hanaa N, Mahmoud, Ayman M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933570/
https://ncbi.nlm.nih.gov/pubmed/27418808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S109287
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