Tissue inflammation and nitric oxide-mediated alterations in cardiovascular function are major determinants of endotoxin-induced insulin resistance

BACKGROUND: Endotoxin (i.e. LPS) administration induces a robust inflammatory response with accompanying cardiovascular dysfunction and insulin resistance. Overabundance of nitric oxide (NO) contributes to the vascular dysfunction. However, inflammation itself also induces insulin resistance in skel...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cardiovasc Diabetol
Päätekijät: House, Lawrence M., Morris, Robert T., Barnes, Tammy M., Lantier, Louise, Cyphert, Travis J., McGuinness, Owen P., Otero, Yolanda F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2015
Aiheet:
Original Investigation
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484635/
https://ncbi.nlm.nih.gov/pubmed/25986700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-015-0223-2
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