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Pathway-selective Insulin Resistance and Metabolic Disease: The Importance of Nutrient Flux
Hepatic glucose and lipid metabolism are altered in metabolic disease (e.g. obesity, metabolic syndrome, and Type 2 diabetes). Insulin-dependent regulation of glucose metabolism is impaired. In contrast, lipogenesis, hypertriglyceridemia, and hepatic steatosis are increased. Because insulin promotes...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4110258/ https://ncbi.nlm.nih.gov/pubmed/24907277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R114.576355 |
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