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Pathway-selective Insulin Resistance and Metabolic Disease: The Importance of Nutrient Flux

Hepatic glucose and lipid metabolism are altered in metabolic disease (e.g. obesity, metabolic syndrome, and Type 2 diabetes). Insulin-dependent regulation of glucose metabolism is impaired. In contrast, lipogenesis, hypertriglyceridemia, and hepatic steatosis are increased. Because insulin promotes...

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Detalhes bibliográficos
Main Authors: Otero, Yolanda F., Stafford, John M., McGuinness, Owen P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110258/
https://ncbi.nlm.nih.gov/pubmed/24907277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R114.576355
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