Epigenetic silencing of BCL6B inactivates p53 signaling and causes human hepatocellular carcinoma cell resist to 5-FU

BCL6B is a potential tumor suppressor in human gastric cancer, but the regulation and mechanism of BCL6B in human hepatocellular carcinogenesis remain unclear. This study is to explore the epigenetic change and mechanism of BCL6B in human hepatocellular carcinoma (HCC). Nineteen hepatic cancer cell...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Li, Xin, Yu, Jie, Brock, Malcolm V., Tao, Qian, Herman, James G., Liang, Ping, Guo, Mingzhou
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484475/
https://ncbi.nlm.nih.gov/pubmed/25909168
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