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Epigenetic silencing of TMEM176A activates ERK signaling in human hepatocellular carcinoma
BACKGROUND: The role of TMEM176A in human hepatocellular carcinoma (HCC) is unknown. This study explored the epigenetic regulation and function of TMEM176A in human HCC. MATERIALS AND METHODS: Twelve HCC cell lines and 126 cases of primary cancer were analyzed. Methylation-specific PCR, immunohistoc...
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| Publicado no: | Clin Epigenetics |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6219251/ https://ncbi.nlm.nih.gov/pubmed/30400968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-018-0570-4 |
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