Epigenetic silencing of DACH1 induces the invasion and metastasis of gastric cancer by activating TGF-β signalling

Gastric cancer (GC) is the fourth most common malignancy in males and the fifth most common malignancy in females worldwide. DACH1 is frequently methylated in hepatic and colorectal cancer. To further understand the regulation and mechanism of DACH1 in GC, eight GC cell lines, eight cases of normal...

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Vydáno v:J Cell Mol Med
Hlavní autoři: Yan, Wenji, Wu, Kongming, Herman, James G, Brock, Malcolm V, Zhou, Yusen, Lu, Youyong, Zhang, Zhiqian, Yang, Yunsheng, Guo, Mingzhou
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2014
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302654/
https://ncbi.nlm.nih.gov/pubmed/24912879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12325
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