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Lipin-1 regulates cancer cell phenotype and is a potential target to potentiate rapamycin treatment

Lipogenesis inhibition was reported to induce apoptosis and repress proliferation of cancer cells while barely affecting normal cells. Lipins exhibit dual function as enzymes catalyzing the dephosphorylation of phosphatidic acid to diacylglycerol and as co-transcriptional regulators. Thus, they are...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncotarget
Päätekijät: Brohée, Laura, Demine, Stéphane, Willems, Jérome, Arnould, Thierry, Colige, Alain C., Deroanne, Christophe F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Impact Journals LLC 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484455/
https://ncbi.nlm.nih.gov/pubmed/25834103
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