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Insulin-stimulated phosphorylation of lipin mediated by the mammalian target of rapamycin

The phosphorylation of a previously uncharacterized protein of apparent M(r) ≈ 140,000 was found to be increased when rat adipocytes were incubated with insulin. The sequences of peptides generated by digesting the protein with trypsin matched perfectly with sequences in mouse lipin. Lipin is the pr...

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Autors principals: Huffman, Todd A., Mothe-Satney, Isabelle, Lawrence, John C.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC117427/
https://ncbi.nlm.nih.gov/pubmed/11792863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.022634399
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