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Insulin-stimulated phosphorylation of lipin mediated by the mammalian target of rapamycin

The phosphorylation of a previously uncharacterized protein of apparent M(r) ≈ 140,000 was found to be increased when rat adipocytes were incubated with insulin. The sequences of peptides generated by digesting the protein with trypsin matched perfectly with sequences in mouse lipin. Lipin is the pr...

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Detalhes bibliográficos
Main Authors: Huffman, Todd A., Mothe-Satney, Isabelle, Lawrence, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC117427/
https://ncbi.nlm.nih.gov/pubmed/11792863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.022634399
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