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Insulin-stimulated phosphorylation of lipin mediated by the mammalian target of rapamycin

The phosphorylation of a previously uncharacterized protein of apparent M(r) ≈ 140,000 was found to be increased when rat adipocytes were incubated with insulin. The sequences of peptides generated by digesting the protein with trypsin matched perfectly with sequences in mouse lipin. Lipin is the pr...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Huffman, Todd A., Mothe-Satney, Isabelle, Lawrence, John C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2002
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC117427/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11792863/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.022634399
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