Chronic liver inflammation modifies DNA methylation at the precancerous stage of murine hepatocarcinogenesis

Chronic liver inflammation precedes the majority of hepatocellular carcinomas (HCC). Here, we explore the connection between chronic inflammation and DNA methylation in the liver at the late precancerous stages of HCC development in Mdr2(−/−) (Mdr2/Abcb4-knockout) mice, a model of inflammation-media...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Stoyanov, Evgeniy, Ludwig, Guy, Mizrahi, Lina, Olam, Devorah, Schnitzer-Perlman, Temima, Tasika, Elena, Sass, Gabriele, Tiegs, Gisa, Jiang, Yong, Nie, Ting, Kohler, James, Schinazi, Raymond F., Vertino, Paula M., Cedar, Howard, Galun, Eithan, Goldenberg, Daniel
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2015
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484438/
https://ncbi.nlm.nih.gov/pubmed/25918251
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