Chronic liver inflammation modifies DNA methylation at the precancerous stage of murine hepatocarcinogenesis

Chronic liver inflammation precedes the majority of hepatocellular carcinomas (HCC). Here, we explore the connection between chronic inflammation and DNA methylation in the liver at the late precancerous stages of HCC development in Mdr2(−/−) (Mdr2/Abcb4-knockout) mice, a model of inflammation-media...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Stoyanov, Evgeniy, Ludwig, Guy, Mizrahi, Lina, Olam, Devorah, Schnitzer-Perlman, Temima, Tasika, Elena, Sass, Gabriele, Tiegs, Gisa, Jiang, Yong, Nie, Ting, Kohler, James, Schinazi, Raymond F., Vertino, Paula M., Cedar, Howard, Galun, Eithan, Goldenberg, Daniel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2015
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484438/
https://ncbi.nlm.nih.gov/pubmed/25918251
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