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Runx2 Expression in Smooth Muscle Cells Is Required for Arterial Medial Calcification in Mice
Arterial medial calcification (AMC) is a hallmark of aging, diabetes, and chronic kidney disease. Smooth muscle cell (SMC) transition to an osteogenic phenotype is a common feature of AMC, and is preceded by expression of runt-related transcription factor 2 (Runx2), a master regulator of bone develo...
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| Udgivet i: | Am J Pathol |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Investigative Pathology
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4484217/ https://ncbi.nlm.nih.gov/pubmed/25987250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.03.020 |
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