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Runx2/Cbfa1, but not loss of Myocardin, is Required for Smooth Muscle Cell Lineage Reprogramming toward Osteochondrogenesis

Vascular calcification is a major risk factor for cardiovascular morbidity and mortality. Smooth muscle cells (SMCs) may play an important role in vascular cartilaginous metaplasia and calcification via reprogramming to the osteochondrogenic state. To study whether SM lineage reprogramming and thus...

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Detalhes bibliográficos
Main Authors: Speer, Mei Y., Li, Xianwu, Hiremath, Pranoti G., Giachelli, Cecilia M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895022/
https://ncbi.nlm.nih.gov/pubmed/20564193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22607
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