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Amyloid-β immunization enhances neurogenesis and cognitive ability in neonatal mice

Whether Aβ actually has a physiological as well as a pathological role is not known. In order to investigate the effect of endogenous Aβ, wild type C57BL/6 mice were immunized with human or mouse derived Aβ1-42. The anti-Aβ antibody concentrations were increased in both treated groups. Compared to t...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Med
Main Authors: Chen, Hongguang, Wang, Min, Jiao, Aihong, Tang, Guotai, Zhu, Wei, Zou, Peng, Li, Tuo, Cui, Guangqiang, Gong, Peiyou
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483988/
https://ncbi.nlm.nih.gov/pubmed/26131110
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