HLA-DQA1 and PLCG2 Are Candidate Risk Loci for Childhood-Onset Steroid-Sensitive Nephrotic Syndrome

Steroid-sensitive nephrotic syndrome (SSNS) accounts for >80% of cases of nephrotic syndrome in childhood. However, the etiology and pathogenesis of SSNS remain obscure. Hypothesizing that coding variation may underlie SSNS risk, we conducted an exome array association study of SSNS. We enrolled...

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Publicat a:J Am Soc Nephrol
Autors principals: Gbadegesin, Rasheed A., Adeyemo, Adebowale, Webb, Nicholas J.A., Greenbaum, Larry A., Abeyagunawardena, Asiri, Thalgahagoda, Shenal, Kale, Arundhati, Gipson, Debbie, Srivastava, Tarak, Lin, Jen-Jar, Chand, Deepa, Hunley, Tracy E., Brophy, Patrick D., Bagga, Arvind, Sinha, Aditi, Rheault, Michelle N., Ghali, Joanna, Nicholls, Kathy, Abraham, Elizabeth, Janjua, Halima S., Omoloja, Abiodun, Barletta, Gina-Marie, Cai, Yi, Milford, David D., O'Brien, Catherine, Awan, Atif, Belostotsky, Vladimir, Smoyer, William E., Homstad, Alison, Hall, Gentzon, Wu, Guanghong, Nagaraj, Shashi, Wigfall, Delbert, Foreman, John, Winn, Michelle P.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2015
Matèries:
Clinical Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483579/
https://ncbi.nlm.nih.gov/pubmed/25349203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014030247
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