Lovastatin-Induced Phosphatidylinositol-4-Phosphate 5-Kinase Diffusion from Microvilli Stimulates ROMK Channels

We recently showed that lovastatin attenuates cyclosporin A (CsA)-induced damage of cortical collecting duct (CCD) principal cells by reducing intracellular cholesterol. Previous studies showed that, in cell expression models or artificial membranes, exogenous cholesterol directly inhibits inward re...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Liu, Bing-Chen, Yang, Li-Li, Lu, Xiao-Yu, Song, Xiang, Li, Xue-Chen, Chen, Guangping, Li, Yichao, Yao, Xincheng, Humphrey, Donald R., Eaton, Douglas C., Shen, Bao-Zhong, Ma, He-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2015
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483575/
https://ncbi.nlm.nih.gov/pubmed/25349201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013121326
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