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Lovastatin inhibits human B lymphoma cell proliferation by reducing intracellular ROS and TRPC6 expression

Clinical evidence suggests that statins reduce cancer incidence and mortality. However, there is lack of in vitro data to show the mechanism by which statins can reduce the malignancies of cancer cells. We used a human B lymphoma Daudi cells as a model and found that lovastatin inhibited, whereas ex...

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Detalhes bibliográficos
Main Authors: Song, Xiang, Liu, Bing-Chen, Lu, Xiao-Yu, Yang, Li-Li, Zhai, Yu-Jia, Eaton, Amity F., Thai, Tiffany L., Eaton, Douglas C., Ma, He-Ping, Shen, Bao-Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015521/
https://ncbi.nlm.nih.gov/pubmed/24518247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2014.02.002
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