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Acute ethanol induces apoptosis by stimulating TRPC6 via elevation of superoxide in oxygenated podocytes

Our recent studies indicate that hydrogen peroxide (H(2)O(2)) only at high concentrations can cause oxidative stress in renal epithelial cells and induce apoptosis of podocytes. Consistently, the present study shows that H(2)O(2), even at 1 mM, failed to induce intracellular oxidative stress and apo...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Lu, Xiao-Yu, Liu, Bing-Chen, Wang, Li-Hua, Yang, Li-Li, Bao, Qing, Zhai, Yu-Jia, Alli, Abdel A., Thai, Tiffany L., Eaton, Douglas C., Wang, Wei-Zhi, Ma, He-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441224/
https://ncbi.nlm.nih.gov/pubmed/25601712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2015.01.007
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