Reduced efficiency of sarcolipin-dependent respiration in myocytes from humans with severe obesity

OBJECTIVE: Sarcolipin (SLN) regulates muscle energy expenditure through its action on sarco/endoplasmic reticulum Ca(2+)-ATPase (SERCA) pump. It is unknown whether SLN-dependent respiration has relevance to human obesity, but whole-transcriptome gene expression profiling revealed that SLN was more h...

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Publicado en:Obesity (Silver Spring)
Main Authors: Paran, Christopher W., Verkerke, Anthony R.P., Heden, Timothy D., Park, Sanghee, Zou, Kai, Lawson, Heather A., Song, Haowei, Turk, John, Houmard, Joseph A., Funai, Katsuhiko
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483165/
https://ncbi.nlm.nih.gov/pubmed/25970801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.21123
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