Druggable targets in pediatric neurocutaneous melanocytosis: Molecular and drug sensitivity studies in xenograft and ex vivo tumor cell culture to identify agents for therapy

BACKGROUND: Neurocutaneous melanocytosis (NCM) is a rare congenital disorder that presents with pigmented cell lesions of the brain or leptomeninges in children with large or multiple congenital melanocytic nevi. Although the exact pathological processes involved are currently unclear, NCM appears t...

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Библиографические подробности
Опубликовано в: :Neuro Oncol
Главные авторы: Ruan, Yibing, Kovalchuk, Anna, Jayanthan, Aarthi, Lun, Xueqing, Nagashima, Yoji, Kovalchuk, Olga, Wright, James R., Pinto, Alfredo, Kirton, Adam, Anderson, Ronald, Narendran, Aru
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2015
Предметы:
Basic and Translational Investigations
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483116/
https://ncbi.nlm.nih.gov/pubmed/25395461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou310
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