Druggable targets in pediatric neurocutaneous melanocytosis: Molecular and drug sensitivity studies in xenograft and ex vivo tumor cell culture to identify agents for therapy

BACKGROUND: Neurocutaneous melanocytosis (NCM) is a rare congenital disorder that presents with pigmented cell lesions of the brain or leptomeninges in children with large or multiple congenital melanocytic nevi. Although the exact pathological processes involved are currently unclear, NCM appears t...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Ruan, Yibing, Kovalchuk, Anna, Jayanthan, Aarthi, Lun, Xueqing, Nagashima, Yoji, Kovalchuk, Olga, Wright, James R., Pinto, Alfredo, Kirton, Adam, Anderson, Ronald, Narendran, Aru
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483116/
https://ncbi.nlm.nih.gov/pubmed/25395461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou310
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