Druggable targets in pediatric neurocutaneous melanocytosis: Molecular and drug sensitivity studies in xenograft and ex vivo tumor cell culture to identify agents for therapy

BACKGROUND: Neurocutaneous melanocytosis (NCM) is a rare congenital disorder that presents with pigmented cell lesions of the brain or leptomeninges in children with large or multiple congenital melanocytic nevi. Although the exact pathological processes involved are currently unclear, NCM appears t...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Neuro Oncol
Main Authors: Ruan, Yibing, Kovalchuk, Anna, Jayanthan, Aarthi, Lun, Xueqing, Nagashima, Yoji, Kovalchuk, Olga, Wright, James R., Pinto, Alfredo, Kirton, Adam, Anderson, Ronald, Narendran, Aru
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2015
נושאים:
Basic and Translational Investigations
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483116/
https://ncbi.nlm.nih.gov/pubmed/25395461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou310
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