Profiling pathway‐specific novel therapeutics in preclinical assessment for central nervous system atypical teratoid rhabdoid tumors (CNS ATRT): Favorable activity of targeting EGFR‐ ErbB2 signaling with lapatinib

Despite intensifying multimodal treatments, children with central nervous system atypical teratoid/rhabdoid tumor (CNS ATRT) continue to endure unacceptably high mortality rates. At present, concerted efforts are focusing on understanding the characteristic INI1 mutation and its implications for the...

詳細記述

保存先:
書誌詳細
出版年:Mol Oncol
主要な著者: Singh, Anjali, Lun, Xueqing, Jayanthan, Aarthi, Obaid, Halah, Ruan, Yibing, Strother, Douglas, Chi, Susan N., Smith, Amy, Forsyth, Peter, Narendran, Aru
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2013
主題:
Papers
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528492/
https://ncbi.nlm.nih.gov/pubmed/23375777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.01.001
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