Development of a Sox2 reporter system modeling cellular heterogeneity in glioma

BACKGROUND: Malignant gliomas are complex systems containing a number of factors that drive tumor initiation and progression, including genetic aberrations that lead to extensive cellular heterogeneity within the neoplastic compartment. Mouse models recapitulate these genetic aberrations, but readil...

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Dades bibliogràfiques
Publicat a:Neuro Oncol
Autors principals: Stoltz, Kevin, Sinyuk, Maksim, Hale, James S., Wu, Qiulian, Otvos, Balint, Walker, Kiera, Vasanji, Amit, Rich, Jeremy N., Hjelmeland, Anita B., Lathia, Justin D.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
Matèries:
Basic and Translational Investigations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483103/
https://ncbi.nlm.nih.gov/pubmed/25416826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou320
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