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The impact of coexisting genetic mutations on murine optic glioma biology

BACKGROUND: Children with the neurofibromatosis type 1 (NF1) tumor predisposition syndrome are prone to the development of optic pathway gliomas resulting from biallelic inactivation of the NF1 gene. Recent studies have revealed the presence of other molecular alterations in a small portion of these...

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發表在:Neuro Oncol
Main Authors: Kaul, Aparna, Toonen, Joseph A., Gianino, Scott M., Gutmann, David H.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482850/
https://ncbi.nlm.nih.gov/pubmed/25246427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou287
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