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The impact of coexisting genetic mutations on murine optic glioma biology

BACKGROUND: Children with the neurofibromatosis type 1 (NF1) tumor predisposition syndrome are prone to the development of optic pathway gliomas resulting from biallelic inactivation of the NF1 gene. Recent studies have revealed the presence of other molecular alterations in a small portion of these...

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Bibliografski detalji
Izdano u:Neuro Oncol
Glavni autori: Kaul, Aparna, Toonen, Joseph A., Gianino, Scott M., Gutmann, David H.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482850/
https://ncbi.nlm.nih.gov/pubmed/25246427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou287
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