TRIM30α Is a Negative-Feedback Regulator of the Intracellular DNA and DNA Virus-Triggered Response by Targeting STING

Uncontrolled immune responses to intracellular DNA have been shown to induce autoimmune diseases. Homeostasis regulation of immune responses to cytosolic DNA is critical for limiting the risk of autoimmunity and survival of the host. Here, we report that the E3 ubiquitin ligase tripartite motif prot...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:PLoS Pathog
Hauptverfasser: Wang, Yanming, Lian, Qiaoshi, Yang, Bo, Yan, Shanshan, Zhou, Haiyan, He, Lan, Lin, Guomei, Lian, Zhexiong, Jiang, Zhengfan, Sun, Bing
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482643/
https://ncbi.nlm.nih.gov/pubmed/26114947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005012
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge